l tyr Search Results


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MedChemExpress amino acid
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Aladdin Scientific Corporation l arginine
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
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Biosynth Carbosynth fmoc 3 iodo l tyr oh
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
Fmoc 3 Iodo L Tyr Oh, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International boc ltyrosine methyl ester
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
Boc Ltyrosine Methyl Ester, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International inc fmoc 3 4 dimethoxy l phenylalanine dmf chem impex
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
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Chem Impex International fmoc l d 4 chlorotyrosine chem impex
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
Fmoc L D 4 Chlorotyrosine Chem Impex, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International fmoc l tyr tbu oh
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
Fmoc L Tyr Tbu Oh, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International mono benzyl protected phosphotyrosine chem impex
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
Mono Benzyl Protected Phosphotyrosine Chem Impex, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International 3 nitro l tyrosine ethyl ester
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
3 Nitro L Tyrosine Ethyl Ester, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International usual amino acids
Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of <t>L‐arginine‐AP</t> mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.
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Image Search Results


Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of L‐arginine‐AP mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.

Journal: Clinical and Translational Medicine

Article Title: Milk fat globule—EGF factor 8/ATP‐binding cassette subfamily E member 1 axis maintains mitophagy flux homeostasis to suppress ferroptosis in acute pancreatitis

doi: 10.1002/ctm2.70619

Figure Lengend Snippet: Inhibition of ferroptosis antagonised the aggravating effect of milk fat globule—epidermal growth factor 8 knockout (MFG‐E8‐KO) on experimental acute pancreatitis (AP). (A) Representative images of haematoxylin and eosin (H&E) staining of the pancreas (200×). (B) Pancreatic injury scores. (C) Serum amylase levels. (D) Serum lactate dehydrogenase (LDH) levels. (E) Serum tumour necrosis factor‐alpha (TNF‐α) levels. (F) Serum interleukin‐6 (IL‐6) levels. (G) Representative images of Myeloperoxidase (MPO) staining. (H) Quantitative of MPO staining. (I) Iron levels in the pancreas. (J and K) Representative images and relative fluorescence intensity of dihydroethidium (DHE) staining in the pancreas. (L) Malondialdehyde (MDA) levels in the pancreas. (M) GSH‐Px enzyme activity. (N) Ultrastructural alterations in the pancreas. (O and P) Western blot analysis of the PTGS2 and glutathione peroxidase (GPX4) expression level in the pancreas. (Q and R) Western blot analysis of the P62 and LC3B expression level in the pancreas. (S) Five‐day survival of L‐arginine‐AP mice. (T) Five‐day survival of cerulein + LPS‐AP mice. n = 4‒15, error bars indicate the SEM; * p < .05 versus WT‐AP; # p < .05 versus KO‐AP. Fer‐1, Ferrostatin‐1; L‐arg, L‐arginine; TEM, transmission electron microscopy; WT, wild type.

Article Snippet: Arginine‐induced AP models were established in mice via intraperitoneal injection of L‐arginine (4 g/kg, cat. no. A640158, Aladdin Scientific) at 2 h intervals.

Techniques: Inhibition, Knock-Out, Staining, Fluorescence, Activity Assay, Western Blot, Expressing, Transmission Assay, Electron Microscopy